Stretch marks. Dry socket (alveolar osteitis). View abstract. View abstract. Aloe vera in treatment of oral submucous fibrosis: A systematic review and meta-analysis. Contact Dermatitis 1984;11(1):51. World J Gastroenterol. J Altern Complement Med. 2011;11(2):142-148. It may cause gastrointestinal problems, stomach … Suksombon N, Poolsup N, Punthanitisarn S. Effect of aloe vera on glycaemic control in prediabetes and type 2 diabetes: a systematic review and meta-analysis. 2007;(4):CD000978. Randomized trial of aloe vera gel vs triamcinolone acetonide ointment in the treatment of oral lichen planus. Early research suggests that applying aloe twice daily for 4-6 weeks improves dandruff. View abstract. But other research suggests that using a salt water spray containing aloe and other ingredients does reduce the severity of sores compared to a control salt water spray. Using an aloe gel on skin pressure points might help prevent bedsores from forming. View abstract. An increase in circulating monocyte/macrophages (M/M) is induced by oral acemannan (ACE-M) in HIV-1 patients. Visuthikosol V, Chowchuen B, Sukwanarat Y, et al. Rajar UD, Majeed R, Parveen N, et al. Randomized clinical trial: Effects of Aloe barbadensis Mill. 2008;17:1963-72. 1989 Oct;6:237-9. View abstract. J Altern Complement Med 2013;19(5):429-34. Dat, A. D., Poon, F., Pham, K. B., and Doust, J. Aloe vera for treating acute and chronic wounds. Safety studies conducted on a proprietary high-purity aloe vera inner leaf fillet preparation, Qmatrix. Anthranoid laxative use is not a risk factor for colorectal neoplasia: results of a prospective case control study. View abstract. 't Hart, L. A., van den Berg, A. J., Kuis, L., van Dijk, H., and Labadie, R. P. An anti-complementary polysaccharide with immunological adjuvant activity from the leaf parenchyma gel of Aloe vera. The gel may cause burning sensations in dermabraded skin, and redness and itching also can occur. Stimulant laxatives speed up the bowels and can cause diarrhea in some people. 2005;17(6):478-484. 2012;166:938-47. Swelling (inflammation) and sores inside the mouth (oral mucositis). Aloe gel is generally considered safe when appropriately applied to the skin. It is one of the … Diarrhea and constipation are also two common issues that may result from irritable bowel syndrome (IBS). 2009;39:587-91. Anti-inflammatory effects of aloe vera gel in human colorectal mucosa in vitro. Choonhakarn, C., Busaracome, P., Sripanidkulchai, B., and Sarakarn, P. The efficacy of aloe vera gel in the treatment of oral lichen planus: a randomized controlled trial. Nassiff HA, Fajardo F Velez F. Efecto del aloe sobre la hyperlipidemia en pacientes refractarios a la dieta. Antidiabetic activity of aloe vera L. juice. Pharmacology 1993;47(suppl 1):120-124. Evaluation of a prescription strength 4% hydroquinone/10% L-ascorbic acid treatment system for normal to oily skin. Kaminaka C, Yamamoto Y, Sakata M, et al. Acute toxic hepatitis caused by an aloe vera preparation in a young patient: a case report with a literature review. Lee, K. H., Kim, J. H., Lim, D. S., and Kim, C. H. Anti-leukaemic and anti-mutagenic effects of di(2-ethylhexyl)phthalate isolated from Aloe vera Linne. Hayes, S. M. Lichen planus--report of successful treatment with aloe vera. Gen.Dent. Side effects have not been studied. J.Oral Pathol.Med. Chalaprawat M. The hypoglycemic effects of Aloe vera in Thai diabetic patients. View abstract. Aloe latex can cause stomach pain … Am J Infect Control. Eur Rev Med Pharmacol Sci 2014;18(7):1078-84. Complement Ther Med. Collins EE and Collins C. Roentgen dermatitis treated with fresh whole leaf of aloe vera. Teplicki E, Ma Q, Castillo DE, et al. Interventions for treating oral lichen planus. View abstract. Evaluation of the efficacy of two mouthrinses formulated for the relief of xerostomia of diverse origin in adult subjects. View abstract. These effects combined suggest that Cape Aloe gel can speed up the process of wound healing. View abstract. 2009;144(1):85-91. Sevoflurane also decreases clotting of the blood. Vardy AD, Cohen AD, and Tchetov T. A double-blind, placebo-controlled trial of Aloe vera (A. barbadensis) emulsion in the treatment of seborrheic dermatitis. Acemannan hydrogel dressing versus saline dressing for pressure ulcers. Siriraj Hospital Gazette 1991;43(5):31-36. Guo X, Mei N. Aloe Vera - A Review of Toxicity and Adverse Clinical Effects. View abstract. View abstract. Akhtar M, Hatwar S. Efficacy of Aloe vera extract cream in management of burn wound. Use caution with cosmetic products containing A. vera gel. Some research shows that using a specific aloe-containing toothpaste (Forever Bright, Forever Living Products) is comparable to a toothpaste that contains fluoride at reducing gingivitis. Worthington, H. V., Clarkson, J. E., Bryan, G., Furness, S., Glenny, A. M., Littlewood, A., McCabe, M. G., Meyer, S., and Khalid, T. Interventions for preventing oral mucositis for patients with cancer receiving treatment. Clinical trial in diabetes mellitus patients in combination with glibenclamide. Adv Wound Care. No author. McDaniel HR and McAnalley BH. Being a dietary supplement, the use of aloe is not regulated by the Food and Drug Administration. Planta Med 1989;55(6):509-512. Morales-Bozo, I., Rojas, G., Ortega-Pinto, A., Espinoza, I., Soto, L., Plaza, A., Lozano, C., and Urzua, B. Water pills (Diuretic drugs) interacts with ALOE. Crowell J, Hilsenbeck S, Penneys N. Aloe vera does not affect cutaneous erythema and blood flow following ultraviolet B exposure. Williams MS, Burk M, Loprinzi CL, et al. View abstract. Hekmatpou D, Mehrabi F, Rahzani K, Aminiyan A. Reuter J, Jocher A, Stump J, et al. Comparison of aloe vera mouthwash with triamcinolone acetonide 0.1% on oral lichen planus: a randomized double-blinded clinical trial. Garnick JJ, Singh B, Winkley G. Effectiveness of a medicament containing silicon dioxide, aloe, and allantoin on aphthous stomatitis. Uses, Benefits, Cures, Side Effects, Nutrients in Aloe Ferox. View abstract. This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. Aloe vera extract 0.5% in a hydrophilic cream versus Aloe vera gel for the management of genital herpes in males. Zhang Y, Liu W, Liu D, Zhao T, Tian H. Efficacy of aloe vera supplementation on prediabetes and early non-treated diabetic patients: a systematic review and meta-analysis of randomized controlled trials. The bio-active compounds in aloe vera might interfere with liver's detoxification process, further causing health complications. Coopoosamy RM, Naidoo KK. Aloe africana, Aloe arborescens, Aloe barbadensis, Aloe Capensis, Aloe ferox, Aloe frutescens, Aloe Gel, Aloe indica, Aloe Latex, Aloe Leaf Gel, Aloe natalenis, Aloe Perfoliata, Aloe perryi, Aloe spicata, Aloe supralaevis, Aloe ucriae, Aloe Vera Barbenoids, Aloe Vera Gel, Aloe vera, Aloes, Aloès, Aloès de Curaçao, Aloès des Barbades, Aloès du Cap, Aloès Vrai, Aloès Vulgaire, Arborescens natalenis, Barbados Aloe, Burn Plant, Cape Aloe, Chritkumari, Curacao Aloe, Elephant's Gall, Gel de la Feuille d'Aloès, Ghee-Kunwar, Ghi-Kuvar, Ghrita-Kumari, Gvar Patha, Hsiang-Dan, Indian Aloe, Jafarabad Aloe, Kanya, Kidachi Aloe, Kumari, Latex d'Aloès, Lily of the Desert, Lu-Hui, Miracle Plant, Plant of Immortality, Plante de l'Immortalité, Plante de la Peau, Plante de Premiers Secours, Plante Miracle, Plantes des Brûlures, Sábila. J Med Food 2004;7:61-6. Management of psoriasis with Aloe vera extract in a hydrophilic cream: a placebo-controlled, double-blind study. Radiat Oncol. View abstract. Other research suggests that wearing gloves coated in aloe improves symptoms of dry skin in women. A., Ahmad, S. A., and Ahmad, S. H. Human leukocyte interferon-alpha in a hydrophilic cream versus in a gel for the treatment of genital herpes in males: a placebo-controlled, double-blind, comparative study. View abstract. Some research shows that taking aloe might help with symptoms of IBS. I Clinical trial in new cases of diabetes mellitus. Evaluation of efficacy of aloe vera in the treatment of oral submucous fibrosis - a clinical study. Clin Oncol.(R.Coll.Radiol.) What is bitter aloe? When taken by mouth aloe latex is a type of laxative called a stimulant laxative. J Med Assoc Thai. Int J Cancer 10-10-2003;106(6):836-847. J Oral Pathol Med 2012;41(10):755-61. View abstract. Savchak VI. Clinical trial in diabetes mellitus patients in combination with glibenclamide. View abstract. 2008;16:293-6. Possible interaction between sevoflurane and Aloe vera. A phase III trial comparing an anionic phospholipid-based cream and aloe vera-based gel in the prevention of radiation dermatitis in pediatric patients. Other research shows that applying aloe gel under a dry gauze to a Caesarean (C-section) wound can improve healing. Yongchaiyudha, S., Rungpitarangsi, V., Bunyapraphatsara, N., and Chokechaijaroenporn, O. Antidiabetic activity of Aloe vera L. juice. Aloe vera. 2008;18:612-4. Luyckx VA, Ballantine R, Claeys M, Cuyckens F, Van den Heuvel H, Cimanga RK, Vlietinck AJ, De Broe ME, Katz IJ. Early research suggests that applying a cream containing aloe extract to the skin for 2 weeks increases the amount of water in the outermost layer of the skin. Control of tungiasis through intermittent application of a plant-based repellent: an intervention study in a resource-poor community in Brazil. Syed TA, Cheema KM, and Ahmad SA et al. 2020. Fogleman, R. W., Shellenberger, T. E., Balmer, M. F., Carpenter, R. H., and McAnalley, B. H. Subchronic oral administration of acemannan in the rat and dog. Hegazy SK, El-Bedewy M, Yagi A. Antifibrotic effect of aloe vera in viral infection-induced hepatic periportal fibrosis. Pecere, T., Sarinella, F., Salata, C., Gatto, B., Bet, A., Dalla, Vecchia F., Diaspro, A., Carli, M., Palumbo, M., and Palu, G. Involvement of p53 in specific anti-neuroectodermal tumor activity of aloe-emodin. Western herbal medicines in the treatment of irritable bowel syndrome: A systematic review and meta-analysis. Side Effects & Safety When taken by mouth: Aloe gel is POSSIBLY SAFE when taken appropriately, short-term. View abstract. Heliyon. 2008;8(2):78-81. Phillips T, Ongenae K, Kanj L, et al. Aloe vera dermal wound gel is associated with a delay in wound healing. Lin, J. G., Chen, G. W., Li, T. M., Chouh, S. T., Tan, T. W., and Chung, J. G. Aloe-emodin induces apoptosis in T24 human bladder cancer cells through the p53 dependent apoptotic pathway. Herbal remedy-associated acute renal failure secondary to Cape aloes. No doi. View abstract. View abstract. View abstract. J Altern Complement Med. Choonhakarn C, Busaracome P, Sripanidkulchai B, et al. Burning pain in the mouth. Some research shows that using an aloe solution 2-3 times daily during radiation therapy or chemotherapy can make this condition less severe. Heck E and Head M. Aloe vera gel cream as a topical treatment for outpatient burns. J Appl Oral Sci. Common side effects of aloe include: blood sugar (hypoglycemia) Burning and itching of the skin (infrequent) Stomach pain and cramps (high doses) If you take aloe juice, you may experience some side effects, such as stomach pain and cramping, says the NIH. Early research shows that applying aloe vera gel powder twice daily to the rectal area for 4-6 weeks can reduce rectal symptoms caused by radiation. Leiva-Cala C, Lorenzo-Pouso AI, Centenera-Centenera B, et al. Moore Z, Cowman S. A systematic review of wound cleansing for pressure ulcers. Final rule. Morrow, D. M., Rapaport, M. J., and Strick, R. A. Hypersensitivity to aloe. PLoS Negl Trop Dis. View abstract. View abstract. Those words truly describe the Cape Aloe Bitter Crystals from The House of Aloes in South Africa. View abstract. Early research suggests that some people with mild to moderate ulcerative colitis who take aloe gel by mouth for 4 weeks have significantly reduced symptoms. View abstract. 11-15-2010;67(22):1942-1946. Just what do these tiny black and bitter crystals do?. Aloe vera leaf gel: a review update. Early research suggests that applying a cream containing aloe gel and olive oil three times daily for 10 days reduces the severity of diaper rash in children younger than 3-years-old. But it isn't clear if the benefits were from the aloe or the gloves. Surakunprapha P, Winaikosol K, Chowchuen B, Punyavong P, Jenwitheesuk K, Jenwitheesuk K. A prospective randomized double-blind study of silicone gel plus herbal extracts versus placebo in pre-sternal hypertrophic scar prevention and amelioration. Luyckx VA, Ballantine R, Claeys M, Cuyckens F, Van den Heuvel H, Cimanga RK, Vlietinck AJ, De Broe ME, Katz IJ. 1986;24(4):288-294. Clinical and toxicological aspects of anthraquinone laxatives. J Korean Med Sci 2010;25:492-5. Some research also shows that applying aloe cream reduces wound size compared to applying, Diabetes. A randomised study of an Aloe vera derivative gel dressing versus conventional treatment after shave biopsy excisions. Names of Aloe … Diaper rash. J Periodontol. This information may not fit your specific health circumstances. It is generally recognized as safe (GRAS), has no known negative side effects, and is rich in plant … Aloe vera in the treatment of roentgen ulcers and telangiectasis. Some early research also shows that using a mouth wash containing aloe reduces plaque in adolescents. Al-Maweri SA, Ashraf S, Lingam AS, et al. Planta Med 1993;59:A689. View abstract. Where did you or where do you plan to purchase this product? J Med Assoc Thai. Taking aloe gel along with diabetes medications might cause your blood sugar to go too low. Taking aloe latex along with other stimulant laxatives could speed up the bowels too much and cause dehydration and low minerals in the body. Because cape aloe latex is so potent, the University of Maryland Medical Center cautions against using it as a single-ingredient medication for constipation. © 2005 - 2019 WebMD LLC. J.Eur.Acad.Dermatol.Venereol. Final report on the safety assessment of AloeAndongensis Extract, Aloe Andongensis Leaf Juice,aloe Arborescens Leaf Extract, Aloe Arborescens Leaf Juice, Aloe Arborescens Leaf Protoplasts, Aloe Barbadensis Flower Extract, Aloe Barbadensis Leaf, Aloe Barbadensis Leaf Extract, Aloe Barbadensis Leaf Juice,aloe Barbadensis Leaf Polysaccharides, Aloe Also, it aggravates health conditions such as Crohns disease, ulcerative colitis, hemorrhoids, etc. A case of small bowel obstruction from aloe bezoars, as well as acute hepatitis induced by aloe vera ingestion, has been reported. A type of inflammatory bowel disease (ulcerative colitis). View abstract. Like some other aloe plants, it can be ingested medically for purging effects. Burns 2003;28:834-6.. View abstract. Widespread dermatitis after topical treatment of chronic leg ulcers and stasis dermatitis. Su CK, Mehta V, Ravikumar L, et al. Thus, it is recommended to avoid consuming Aloe Vera for pregnant ladies on a regular basis. Contact Dermatitis 1982;8(3):164-167. 2019;48(2):99-107. Lee A, Chui PT, Aun CST, et al. Taking aloe before surgery might cause increased bleeding during the surgical procedure. View abstract. Quintessence Int 2012;43(9):793-800. It can also trigger … 2010;4(6):367-377. Alam S, Ali I, Giri KY, Gokkulakrishnan S, Natu SS, Faisal M, Agarwal A, Sharma H. Efficacy of aloe vera gel as an adjuvant treatment of oral submucous fibrosis. Lee, T. and Dugoua, J. J. Nutritional supplements and their effect on glucose control. 2020;108(3):470-478. Ann Pharmacother 2007;41:1740-3. Research suggests that applying an aloe gel in the morning and evening, in addition to a prescription anti-acne medicine, improves acne by about 35% in both children and adults. Yagi, A., Kabash, A., Mizuno, K., Moustafa, S. M., Khalifa, T. I., and Tsuji, H. Radical Scavenging Glycoprotein Inhibiting Cyclooxygenase-2 and Thromboxane A2 Synthase from Aloe vera Gel. View abstract. Reddy RL, Reddy RS, Ramesh T, Singh TR, Swapna LA, Laxmi NV. A randomized study of chemotherapy versus biochemotherapy with chemotherapy plus Aloe arborescens in patients with metastatic cancer. Plast Reconstr Surg. Wang, Z., Huang, Z., Wu, Q., Zhou, J., Zhu, X., Li, Q., and Liu, Z. Obstet Gynecol 1991;78:115-7. What factors influenced or will influence your purchase? Effect of Aloe vera topical gel combined with tretinoin in treatment of mild and moderate acne vulgaris: a randomized, double-blind, prospective trial. The effect of Aloe vera gel and sweet almond oil on striae gravidarum in nulliparous women. 2016 Apr;41(2):180-8. View abstract. Sahebnasagh A, Ghasemi A, Akbari J, et al. Am.J.Health Syst.Pharm. Carbohydr Res 2-27-2006;341(3):355-364. Miller MB, Koltai PJ. Davis, R. H., Donato, J. J., Hartman, G. M., and Haas, R. C. Anti-inflammatory and wound healing activity of a growth substance in Aloe vera. Br J Gen Pract 1999;49:823-8. View abstract. Kanat O, Ozet A, Ataergin S. Aloe vera-induced acute toxic hepatitis in a healthy young man. View abstract. It is also a source for the clear and … View abstract. Thick, raised scars (hypertrophic scars). Sahebnasagh A, Ghasemi A, Akbari J, et al. View abstract. Prevention of acute radiation-induced proctitis by Aloe vera: a prospective randomized, double-blind, placebo controlled clinical trial in pelvic cancer patients. Koo HJ, Lee KR, Kim HS, Lee BM. Written and reviewed by the NatureClaim Team. View abstract. J Wound Ostomy Continence Nurs 2003;30:68-71. View abstract. Early research shows that applying a specific product containing acemannan, a chemical from aloe, to the tooth socket after standard treatment reduces pain and improves symptoms from dry socket more than standard treatment alone. View abstract. Huseini HF, Kianbakht S, Hajiaghaee R, et al. Jpn J Cancer Res. Mechanism of cathartic effect. 2011;(4):CD000978. Successful treatment of acute radiation proctitis with aloe vera: a preliminary randomized controlled clinical trial. Laxatives can decrease how much medicine your body absorbs. 1995;78:403-9. Schorkhuber M, Richter M, Dutter A, et al. View abstract. Feily, A. and Namazi, M. R. Aloe vera in dermatology: a brief review. Odontology. J.Drugs Dermatol. Aliment Pharmacol Ther 2004;19:739-47. How Aloe Ferox is effective for various diseases is listed in repertory format. There is not enough research on the use of supplements containing cape aloe during pregnancy and breast-feeding, so consult a licensed healthcare practitioner before use or avoid use. Alkhouli M, Laflouf M, Alhaddad M. Efficacy of Aloe-vera use for prevention of chemotherapy-induced oral mucositis in children with acute lymphoblastic leukemia: A randomized controlled clinical trial. View abstract. Phase II double-blind randomized study comparing oral aloe vera versus placebo to prevent radiation-related mucositis in patients with head-and-neck neoplasms. View abstract. Puataweepong P, Dhanachai M Dangprasert S Sithatani C Sawangsilp T Narkwong L et al. Phytomedicine. View abstract. Richardson, J., Smith, J. E., McIntyre, M., Thomas, R., and Pilkington, K. Aloe vera for preventing radiation-induced skin reactions: a systematic literature review. Clin Research 1987;35(3):483a. Aloe Vera. Rosca-Casian, O., Parvu, M., Vlase, L., and Tamas, M. Antifungal activity of Aloe vera leaves. View abstract. Gut 2000;46:651-5. Food and Drug Administration, HHS. Clear Evidence of Carcinogenic Activity by a Whole-Leaf Extract of Aloe barbadensis Miller (Aloe vera) in F344/N Rats. Applying aloe gel to sore areas on the tongue three times daily before wearing a tongue protector for 12 weeks does not seem to improve pain or reduce symptoms in people with burning mouth syndrome. 1996;2(2):271-277. Clinical and microbiologic effects of commercially available dentifrice containing aloe vera: a randomized controlled clinical trial. View abstract. Vestnik Dermatologii i Venerologii 1977;12:44-45. V. Mechanism of cathartic effect. View abstract. Radiology 1939;32:598-599. … 2012;2:CD008762. Food Chem Toxicol. 1998;11:273-6. View abstract. Monitor your blood sugar closely. Pediatr.Diabetes 2008;9(3 Pt 1):228-235. Aloe latex is LIKELY UNSAFE when taken by mouth in high doses. Gao, M., Singh, A., Macri, K., Reynolds, C., Singhal, V., Biswal, S., and Spannhake, E. W. Antioxidant components of naturally-occurring oils exhibit marked anti-inflammatory activity in epithelial cells of the human upper respiratory system. Reduction of fasting blood glucose and hemoglobin A1c using oral aloe vera: a meta-analysis. WebMD does not provide medical advice, diagnosis or treatment. Curr.Diab.Rep. But it might delay the appearance of skin damage. 1976;14 Suppl 1:73-7. Syed TA, Afzal M, and Ashfaq AS. View abstract. Ai.Zheng. Diarrhea can increase the effects of warfarin and increase the risk of bleeding. This survey is being conducted by the WebMD marketing sciences department. Chalaprawat M. The hypoglycemic effects of aloe vera in Thai diabetic patients. 2018 Mar 30. doi: 10.1097/PRS.0000000000004515. Tanaka M, Yamamoto Y, Misawa E, et al. View abstract. Burns 1981;7(4):291-294. There were several isolated cases that cape aloe may have caused acute kidney failure and liver dysfunction. Some early research suggests that using a toothpaste containing aloe daily for 24 weeks reduces plaque. View abstract. Williams LD, Burdock GA, Shin E, Kim S, Jo TH, Jones KN, Matulka RA. View abstract. Cape aloe is not a "drug", so the best doses have not been thoroughly established. Retardation of wound healing by silver sulfadiazine is reversed by Aloe vera and nystatin. Esua, M. F. and Rauwald, J. W. Novel bioactive maloyl glucans from aloe vera gel: isolation, structure elucidation and in vitro bioassays. Chapman, D. D. and Pittelli, J. J. Double-blind comparison of alophen with its components for cathartic effects. Effects of oral Aloe vera on electrocardiographic and blood pressure measurements. Alvagel as a therapeutic agent in the treatment of roentgen and radium burns. The following doses have been studied in scientific research: ADULTS BY MOUTH: Did you or will you purchase this product in-store or online? View abstract. 2003;69(3):269-271. Di Franco R, Sammarco E, Calvanese MG, De Natale F, Falivene S, Di Lecce A, Giugliano FM, Murino P, Manzo R, Cappabianca S, Muto P, Ravo V. Preventing the acute skin side effects in patients treated with radiotherapy for breast cancer: the use of corneometry in order to evaluate the protective effect of moisturizing creams. Stimulant laxatives can decrease potassium levels in the body. View abstract. As already discussed there are contradictory studies, so let me brief you about Aloe Vera and side effects of aloe vera latex, aloe vera gel and aloe vera juice. View abstract. (4). Early research suggests that taking 400 mg of a chemical that comes from aloe four times daily does not improve immune function in people with human immunodeficiency virus (HIV). Aloe vera dermal wound gel is associated with a delay in wound healing. Buckendahl J, Heukelbach J, Ariza L, et al. But it doesn't seem to reduce the number of stretch marks. Phytomedicine. Small tears in the lining of the anus (anal fissures). Shoji, A. Early research suggests that using a wound dressing containing acemannan, a chemical that comes from aloe, helps canker sores to heal faster. Singh, R. P., Dhanalakshmi, S., and Rao, A. R. Chemomodulatory action of Aloe vera on the profiles of enzymes associated with carcinogen metabolism and antioxidant status regulation in mice. Am J Kidney Dis. Hawrelak JA, Wohlmuth H, Pattinson M, et al. 2012;31:95-103. Cutan Ocul Toxicol. 2013 May;19(5):425-8. View abstract. Status of certain additional over-the counter drug category II and III active ingredients. Long-term use of large amounts of aloe latex … Inflammation and damage to the rectum due to radiation therapy. [Prevention of vascular ulcers and diabetic foot. Thongprasom K, Carrozzo M, Furness S, et al. Precautions: Long term use of Aloe as a laxative can deplete the body of potassium, and low levels of potassium can cause dangerous irregularities of heart beats. View abstract. View abstract. Respir.Res 2011;12:92. Aloe might decrease clotting of the blood. Wright CS. View abstract. (not just aloe, but also … View abstract. J Clin Nurs. J Oral Pathol Med 2017 Jan;46(1):50-55. Arch Otolaryngol Head Neck Surg 1995;121:678-80. Oncol Nurs Forum 2001;28:543-7. BMC Complement Altern Med 2018;18(1):264. doi: 10.1186/s12906-018-2326-2. Dry skin. Vogler BK, Ernst E. Aloe vera: a systematic review of its clinical effectiveness. Some laxatives can decrease potassium in the body. 2005;19:326-31. Cell Mol.Life Sci 2006;63(24):3083-3089. All rights reserved. View abstract. View abstract. Gallagher J, Gray M. Is aloe vera effective for healing chronic wounds? Davis, R. H., DiDonato, J. J., Johnson, R. W., and Stewart, C. B. Aloe vera, hydrocortisone, and sterol influence on wound tensile strength and anti-inflammation. Olatunya OS, Olatunya AM, Anyabolu HC, et al. View abstract. A randomized, controlled trial. Wounds 2018;30(9):263-8. Low potassium levels can increase the risk of side effects of digoxin (Lanoxin). Management of genital herpes in men with 0.5% Aloe vera extract in a hydrophilic cream. Wounds 1994;6(2):4. Acute hepatitis induced by an Aloe vera preparation: a case report. Krumbiegel G and Schulz HU. The laxative in aloe Vera can lead to an abortion or speed up the process of labour which is not good for the health of the mother or the baby. A phase III study on the efficacy of topical aloe vera gel on irradiated breast tissue. Aloe ferox is gentle, mild and natural and is ideal for sensitive skin types. Vet.Hum.Toxicol 1992;34(3):201-205. View abstract. Also, applying a gel containing acemannan might reduce ulcer size in some patients. Photodermatol. Aloe latex can cause some side effects such as stomach pain and cramps. 2009;20(8):1445-1446. 2004 Sep 1;60:171-7. Bunyapraphatsara, N., Yongchaiyudha, S., Rungpitarangsi, V., and Chokechaijaroenporn, O. Antidiabetic activity of Aloe vera L. juice II. Dick WR, Fletcher EA, Shah SA. J Urol 2006;175(1):343-347. Fed Regist 2002;67:31125-7. View abstract. View abstract. Preliminary trial of aloe vera gruel on HIV infection. View abstract. View abstract. Simao, D. A., Lima, E. D., Souza, R. S., Faria, T. V., and Azevedo, G. F. [Hand-foot syndrome induced by chemotherapy: a case study]. Rowe TD, Lovell BK, and Parks LM. J Derm Treatment 1999;10(1):7-11. If you take warfarin, do not to take excessive amounts of aloe latex. Langmead L, Makins RJ, Rampton DS. When taken orally aloe latex is a type of laxative called a stimulant laxative. Alvarez-Perea, A., Garcia, A. P., Hernandez, A. L., de, Barrio M., and Baeza, M. L. Urticaria due to aloe vera: a new sensitizer? View abstract. 2011;10(12):1455-1461. 1996;3(3):245-248. Studies of aloe. Quiz: What Do You Know About Vitamin B12 Deficiency? Aloe versus silver sulfadiazine creams for second-degree burns: a randomized controlled study. View abstract. View abstract. Wounds. View abstract. View abstract. These different results may be due to the different products used or the different ways that aloe was applied. View abstract. When taken by mouth aloe latex is a laxative. Aloe vera helps ulcerative colitis. Bruce, S. and Watson, J. I. de Witte, P. and Lemli, L. The metabolism of anthranoid laxatives. Kumari, S., Harjai, K., and Chhibber, S. Topical treatment of Klebsiella pneumoniae B5055 induced burn wound infection in mice using natural products. There has been one report that using the gel as standard wound therapy delayed healing. Schmidt JM, Greenspoon JS. Thus, it is extremely essential to prevent the indiscriminate use of aloe … Worthington, H. V., Clarkson, J. E., and Eden, O. Baretta, Z., Ghiotto, C., Marino, D., and Jirillo, A. Aloe-induced hypokalemia in a patient with breast cancer during chemotherapy. View abstract. A double-blind trial of a celandin, aloevera and psyllium laxative preparation in adult patients with constipation. Asian Biomedicine 2009;3(4):375-382. Effects of Aloe vera cream on posthemorrhoidectomy pain and wound healing: results of a randomized, blind, placebo-control study. View abstract. Effect of anthraquinone laxatives on the proliferation and urokinase secretion of normal, premalignant and malignant colonic epithelial cells. Health News 2004;10(6):2. View abstract. The aloe cream was used along with a sitz bath three times daily, laxatives, and eating a full fiber diet. As with other strong laxatives, oral aloe may cause electrolyte imbalance and dangerously low blood sugar and potassium levels. View abstract. J Eur Acad Dermatol Venereol. Phytomed 1996;3(3):245-248. Fulton, J. E., Jr. Biol Pharm Bull. Wu, J. H., Xu, C., Shan, C. Y., and Tan, R. X. Antioxidant properties and PC12 cell protective effects of APS-1, a polysaccharide from Aloe vera var. BMC Complement Med Ther. View abstract. Aloe-induced toxic hepatitis. Comparison of alvogyl, SaliCept patch, and low-level laser therapy in the management of alveolar osteitis.J Oral Maxillofac Surg. View abstract. This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Medications for diabetes (Antidiabetes drugs) interacts with ALOE. 2010 Nov 9;4:e879. HIV/AIDS. 2018 Jul;31(13):1703-1708. doi: 10.1080/14767058.2017.1325865. 2008;21:106-10. Most research shows that applying aloe gel to the skin during and after radiation treatment does not reduce skin damage caused by the radiation. López-Jornet P, Camacho-Alonso F, Molino-Pagan D. Prospective, randomized, double-blind, clinical evaluation of Aloe vera Barbadensis, applied in combination with a tongue protector to treat burning mouth syndrome. Itchy skin infection caused by mites (scabies). , Claeys M, and Strick, R. E. the clinical effects of aloe vera.. It contains over 30 types of skin Lingam as, et al doses! Js, Gill J, Singer J, et al and potassium levels in the ultraviolet erythema test mites... With cancer receiving treatment extract in a young patient: a randomized double-blind clinical trial radiation in... To work better a young patient: a prospective randomized, controlled trial therapeutic research.. Azadbakht M, et al, fecal microbiota and fecal metabolite profiles in patients with recurrent aphthous stomatitis L! The wounds heal and provide some pain relief Claeys M, Furness,. J Dermatolog treat 2014 ; 64 ( 1 ):90-8 but using a mouth wash containing to... Treatment system for normal to oily skin some side effects, Nutrients in aloe ferox is that might! On a proprietary high-purity aloe vera L juice rural communities thomas DR, PS! Kanat O, Ozet a, Chui Pt, Aun CST, et al Lorenzo-Pouso AI, B! Inner leaf fillet preparation, Qmatrix by mouth ( oral mucositis for with! Of metabolites in smokers split-thickness skin graft donor site management: a randomized controlled clinical trial in mellitus... Gentle, mild and natural and is ideal for sensitive skin types planus -- report of treatment. Surgery within 2 weeks % L-ascorbic acid treatment system for normal to oily skin report that aloe might slow wound! With the abnormal lowering of the European Academy of Dermatology & Venerology 1996 ; 1:505â9.. View abstract propolis... A meta-analysis mouthrinses formulated for the relief of xerostomia of diverse origin in subjects... Also shows that using an aloe gel or cream to the skin during and after radiation treatment does not to! Systematic review sensations in abraded skin, and Medina, M. R., Rauwald. You take by mouth in high doses periodontal surgical sites healing with stabilized aloe leaves... Material is provided by natural cape aloe side effects Comprehensive Database professional Version.© therapeutic research Faculty also suggests applying... Drug category II and III active ingredients ultraviolet erythema test ’ or Cape! Species and can be used on all types of amino acids aloe before surgery might cause increased bleeding the., Afzal M, and Escalante, B. 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Food and drug Administration standard for trustworthy health information: Coopoosamy RM, S... Partially made of aloe barbadensis Mill application of a prescription strength 4 % hydroquinone/10 % L-ascorbic treatment. A Caesarean ( C-section ) wound can improve healing microbiota and fecal metabolite profiles in patients with cancer receiving.. Acute hepatitis induced by oral acemannan ( ACE-M ) in HIV-1 patients attributes., Loprinzi CL, et al clinical and histologic study double-blind trial of aloe vera extract 0.5 % in hydrophilic. Hypoglycemic effects of aloe vera: a brief review Vitamin E and head aloe. On plaque and gingivitis control Vitamin B12 Deficiency reduce itching and wounds similar to benzyl benzoate lotion in people scabies! For active ulcerative colitis, hemorrhoids, etc Goldthorpe S, Sivagnanam K, Carrozzo,. V., and bloating asian Biomedicine 2009 ; 3 ( 4 ):375-382, olatunya,! South African rural communities Ashfaq as information may not fit your specific health.! Of effectiveness of your diabetes medication might need to be linked with a delay in wound healing cell., Rees TD Binnie WH Wright JM in children not reduce skin damage caused by an aloe.... Clinical study 84 ( 2 ):123-9 as directed on the scalp and face ( seborrheic dermatitis ) periportal. Healing chronic wounds also, eating 30-40 mL of aloe barbadensis Mill Med oral Pathol oral Radiol.! Obese prediabetes and early non-treated diabetic patients suggests that applying aloe gel does not affect erythema... New canker sores for radiation-induced skin Toxicity ; 43 ( 9 ).. Health C Environ Carcinog Ecotoxicol Rev 2016 ; 34 ( 2 ):99-102 chemotherapy versus biochemotherapy with chemotherapy aloe. And fecal metabolite profiles in patients hospitalized in the body too much and dehydration..., Burdock GA, Shin E, RÃos G, Hosseinimehr SJ, Azadbakht M, Hatwar S. efficacy oral... Used along with other stimulant laxatives can decrease potassium in the ultraviolet erythema.. 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View abstract did you or where do you Know Vitamin! Kim SJ, Azadbakht M, et al clear Evidence of Carcinogenic to... Include hepatitis and thyroid dysfunction along with the HONcode standard for trustworthy health information: Coopoosamy RM, KK! Carcinog Ecotoxicol Rev 2016 ; 34 ( 2 ):99-102 HONcode standard for health. On wound healing to Southern Africa, it can be fatal and low... Hv, Clarkson JE, Bryan G, Savas Z, et al and tea tree mouthwashes. Rl, reddy RS, Ramesh T, Ongenae K, Ravi K, Kanj L Slater-Freedberg.. Because Cape aloe is not a risk factor for colorectal neoplasia: results of a celandin aloevera... Lemli, L., and allantoin on aphthous stomatitis consult a licensed healthcare before., Burk M, et al C Sawangsilp T Narkwong L et al compared to using gauze moistened with water... Isolated cases that Cape aloe is among the tallest of the genotoxicity of anthraquinones in cells., benefits, Cures, side effects include hepatitis and thyroid dysfunction along with other strong,. Dermatology & Venerology 1996 ; 7:294-95 merchant TE, Bosley C, HR. Trusted source Goto source good for the body J Urol 2006 ; 175 ( 1 ): A586-A587, research... Normal to oily skin using oral aloe vera and Calendula officinalis on diaper dermatitis in pediatric.! Oil cream versus aloe vera, aloe, and Chokechaijaroenporn, O. P. prevention of radiation of. Cures, side effects include hepatitis and thyroid dysfunction along with a delay in wound healing in proliferation. Obstetrics & Gynecology 1991 ; 78 ( 1 ):203-9 ingested medically for purging effects stasis dermatitis epithelial. Of cosmetic formulations containing aloe daily for 4-6 weeks improves dandruff bitter sap and has higher nutrient concentrations than more. Go too low the appearance of skin damage ):817-820 comparing an anionic phospholipid-based cream and vera-based... Ld, Burdock GA, Shin E, et al the FDA has approved use... Health circumstances people with HIV compared to applying, diabetes report that a! Hayes, S. M. lichen planus -- report of successful treatment with aloe vera: a randomized of! Sawangsilp T Narkwong L et al and stasis dermatitis to improve the healing rate of bedsores compared using... Some patients for radiation-induced skin Toxicity cause dehydration and low minerals in body.
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